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KMID : 1098420110190050388
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Korean Journal of Medicinal Crop Science
2011 Volume.19 No. 5 p.388 ~ p.394
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Antioxidant and Cell Activity Using Extracts of Mume Fructus
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Bae Yu-Kyung
Choe Tae-Boo
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Abstract
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Mume fructus is the roasted fruits of Prunus mume and has been used as traditional chinese medicine. In this study, mume fructus extracts were prepared by three different methods including hot water extract (sample1), fermentation extract using Lactobacillus (Sample2-LP and sample-LA) and ethanol extract (sample3). Total polyphenol and flavonoid contents were improved by fermentation process, compared to water extract. Sample 3 showed the highest activity in DPPH radical scavenging. The cytotoxicity of the sample 2-LP was in the range of 83.3% cell viability at concentration. Mume fructus extracts in a concentration-dependent manner inhibited melanogenesis and NO synthesis was inhibited. Specifically, the extracts fermented by L. plantarum (sample2-LP) showed higher anti-oxidant activity, anti-inflammatory and skin whitening activity than other extracts. It suggests that sample 2-LP could be potentially used as a resource of materials for functional cosmetics.
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KEYWORD
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Mume Fructus, Cosmeceutical Activity, Anti-oxidation, Fermentation
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